Pediatric conjunctival melanoma arising from a compound nevus.

Journal Article (Journal Article)

We present a rare case of conjunctival melanoma in a 9-year-old girl who presented with a conjunctival lesion of the left eye, growth of which was documented by patient photographs. Examination showed a raised pigmented lesion at the temporal limbus, with fine surrounding vessels. Enhanced depth imaging-optical coherence tomography showed no invasion into the sclera. The patient underwent excisional biopsy, and histopathology revealed conjunctival melanoma arising from a nevus with malignant cells that stained positively with markers HMB-45 and Ki-67. Systemic workup was negative for metastatic disease. Conjunctival nevi are the most common melanocytic conjunctival lesions in children and generally demonstrate physiologic growth during adolescence. Thus, there may be a greater risk of misdiagnosis of conjunctival melanoma in a child.

Full Text

Duke Authors

Cited Authors

  • Liu, KC; Mruthyunjaya, P; Proia, AD; Vora, GK

Published Date

  • October 2017

Published In

Volume / Issue

  • 21 / 5

Start / End Page

  • 416 - 418

PubMed ID

  • 28860029

Electronic International Standard Serial Number (EISSN)

  • 1528-3933

Digital Object Identifier (DOI)

  • 10.1016/j.jaapos.2017.04.014


  • eng

Conference Location

  • United States