Thermoreversible hydrogel based on radiation induced copolymerisation of poly(N-isopropyl acrylamide) and poly(ethylene oxide) †

Journal Article

Thermoreversible copolymer hydrogel based on poly(ethylene oxide) and poly(N-isopropyl acrylamide) has been prepared by γ-radiation technique. The utility of 13C n.m.r. spectroscopy in elucidating the structure and copolymer composition has been demonstrated. The volume transition as a function of temperature in these copolymers has been studied by swelling ratio measurements. Unlike poly(ethylene oxide) homopolymer gel, the copolymer gels show first order volume transition in the temperature range of 35-40°C. These gels are easy to synthesise in any shape and size and are found to be having good mechanical strength even in the fully swollen state. They can have poter tial applications in controlled drug delivery, bioseparations and biomedical fields. © 1998 Elsevier Science Ltd. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Bhalerao, VS; Varghese, S; Lele, AK; Badiger, MV

Published Date

  • January 1, 1998

Published In

Volume / Issue

  • 39 / 11

Start / End Page

  • 2255 - 2260

International Standard Serial Number (ISSN)

  • 0032-3861

Digital Object Identifier (DOI)

  • 10.1016/S0032-3861(97)00502-8

Citation Source

  • Scopus