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Immune-mediated inner ear disease.

Publication ,  Journal Article
Stone, JH; Francis, HW
Published in: Curr Opin Rheumatol
January 2000

Immune-mediated inner ear disease (IMIED) is a syndrome that includes the subacute onset of sensorineural hearing loss, often accompanied by vertigo and tinnitus. This constellation of symptoms may occur as a primary disorder in which no other organ involvement is evident, or it may complicate certain systemic conditions, including Wegener's granulomatosis, Cogan's syndrome, polyarteritis nodosa, and systemic lupus erythematosus. The precise disease mechanisms remain undefined, largely because of the difficulty obtaining relevant tissue specimens in untreated patients. However, if treated promptly with aggressive immunosuppression, the devastating sequelae of IMIED may be avoided. In this article, we review the pathophysiology, clinical evaluation, diagnostic testing, and therapy of IMIED.

Duke Scholars

Published In

Curr Opin Rheumatol

DOI

ISSN

1040-8711

Publication Date

January 2000

Volume

12

Issue

1

Start / End Page

32 / 40

Location

United States

Related Subject Headings

  • Labyrinthitis
  • Humans
  • Diagnosis, Differential
  • Arthritis & Rheumatology
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Stone, J. H., & Francis, H. W. (2000). Immune-mediated inner ear disease. Curr Opin Rheumatol, 12(1), 32–40. https://doi.org/10.1097/00002281-200001000-00006
Stone, J. H., and H. W. Francis. “Immune-mediated inner ear disease.Curr Opin Rheumatol 12, no. 1 (January 2000): 32–40. https://doi.org/10.1097/00002281-200001000-00006.
Stone JH, Francis HW. Immune-mediated inner ear disease. Curr Opin Rheumatol. 2000 Jan;12(1):32–40.
Stone, J. H., and H. W. Francis. “Immune-mediated inner ear disease.Curr Opin Rheumatol, vol. 12, no. 1, Jan. 2000, pp. 32–40. Pubmed, doi:10.1097/00002281-200001000-00006.
Stone JH, Francis HW. Immune-mediated inner ear disease. Curr Opin Rheumatol. 2000 Jan;12(1):32–40.

Published In

Curr Opin Rheumatol

DOI

ISSN

1040-8711

Publication Date

January 2000

Volume

12

Issue

1

Start / End Page

32 / 40

Location

United States

Related Subject Headings

  • Labyrinthitis
  • Humans
  • Diagnosis, Differential
  • Arthritis & Rheumatology
  • 3202 Clinical sciences
  • 1103 Clinical Sciences