Topical Review: MACI as an Emerging Technology for the Treatment of Talar Osteochondral Lesions.
Matrix-induced autologous chondrocyte implantation (MACI) is a viable procedure that can be used as both a primary or revision cartilage regenerative procedure in high-functioning individuals without tibiotalar arthritis. Both short-term and midterm follow-up results demonstrate clinical, radiographic, and functional improvements with high rates of return to full activities. Cost remains a chief concern with the use of this technique, but theoretical improvements in the durability of repair with type II cartilage replacement may offer long-term benefits. LEVEL OF EVIDENCE: Level V, expert opinion.
Dekker, TJ; Erickson, B; Adams, SB; Gross, CE
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