Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope.
Journal Article (Journal Article)
Age-related macular degeneration (AMD) is a major cause of vision loss in the elderly. To better study the pathobiology of AMD, postmortem eyes offer an excellent opportunity to correlate optical coherence tomography (OCT) imaging characteristics with histopathology. However, postmortem eyes from autopsy present challenges to standard OCT imaging including opaque anterior segment structures and standard of care autopsy processing resulting in oblique views to the macula. To overcome these challenges, we report a custom periscope attached by a standard mount to an OCT sample arm and demonstrate high quality macular OCT acquisitions in autopsy-processed eyes.
- McNabb, RP; Tian, J; Farsiu, S; Izatt, JA; Lad, EM; Kuo, AN
- September 1, 2017
Volume / Issue
- 8 / 9
Start / End Page
- 4152 - 4159
Pubmed Central ID
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)
- United States