The changing landscape of dermatology practice: melanoma and pump-probe laser microscopy.


Journal Article (Review)

To present current melanoma diagnosis, staging, prognosis, and treatment algorithms and how recent advances in laser pump-probe microscopy will fill in the gaps in our clinical understanding. Expert opinion and significantly cited articles identified in SCOPUS were used in conjunction with a pubmed database search on Melanoma practice guidelines from the last 10 years. Significant advances in melanoma treatment have been made over the last decade. However, proper treatment algorithm and prognostic information per melanoma stage remain controversial. The next step for providers will involve the identification of patient population(s) that can benefit from recent advances. One method of identifying potential patients is through new laser imaging techniques. Pump-probe laser microscopy has been shown to correctly identify nevi from melanoma and furthermore stratify melanoma by aggressiveness. The recent development of effective adjuvant therapies for melanoma is promising and should be utilized on appropriate patient populations that can potentially be identified using pump-probe laser microscopy.

Full Text

Duke Authors

Cited Authors

  • Puza, CJ; Warren, WS; Mosca, PJ

Published Date

  • November 2017

Published In

Volume / Issue

  • 32 / 8

Start / End Page

  • 1935 - 1939

PubMed ID

  • 28890988

Pubmed Central ID

  • 28890988

Electronic International Standard Serial Number (EISSN)

  • 1435-604X

Digital Object Identifier (DOI)

  • 10.1007/s10103-017-2319-2


  • eng

Conference Location

  • England