Recognition and Clinical Presentation of Invasive Fungal Disease in Neonates and Children.

Journal Article (Review;Journal Article)

Invasive fungal diseases (IFDs) are devastating opportunistic infections that result in significant morbidity and death in a broad range of pediatric patients, particularly those with a compromised immune system. Recognizing them can be difficult, because nonspecific clinical signs and symptoms or isolated fever are frequently the only presenting features. Therefore, a high index of clinical suspicion is necessary in patients at increased risk of IFD, which requires knowledge of the pediatric patient population at risk, additional predisposing factors within this population, and the clinical signs and symptoms of IFD. With this review, we aim to summarize current knowledge regarding the recognition and clinical presentation of IFD in neonates and children.

Full Text

Duke Authors

Cited Authors

  • King, J; Pana, Z-D; Lehrnbecher, T; Steinbach, WJ; Warris, A

Published Date

  • September 2017

Published In

Volume / Issue

  • 6 / suppl_1

Start / End Page

  • S12 - S21

PubMed ID

  • 28927201

Pubmed Central ID

  • PMC5907856

Electronic International Standard Serial Number (EISSN)

  • 2048-7207

International Standard Serial Number (ISSN)

  • 2048-7193

Digital Object Identifier (DOI)

  • 10.1093/jpids/pix053


  • eng