Nemaline myopathy associated with hypertrophic cardiomyopathy.


Journal Article

Nemaline myopathy is not usually considered to involve cardiac muscle and rarely is associated with nocturnal hypoventilation. We report a boy, 5 1/2 years of age, with nemaline myopathy who presented with respiratory failure. Echocardiography demonstrated the septum to left ventricular posterior wall ratio to be increased which is consistent with a hypertrophic cardiomyopathy. Because of nocturnal hypoventilation, tracheostomy was placed for ventilatory assistance. A process involving both muscle and nervous tissue may underlie this congenital myopathy; routine cardiac and pulmonary function evaluations may be indicated in these patients.

Full Text

Duke Authors

Cited Authors

  • Van Antwerpen, CL; Gospe, SM; Dentinger, MP

Published Date

  • September 1988

Published In

Volume / Issue

  • 4 / 5

Start / End Page

  • 306 - 308

PubMed ID

  • 3242535

Pubmed Central ID

  • 3242535

International Standard Serial Number (ISSN)

  • 0887-8994

Digital Object Identifier (DOI)

  • 10.1016/0887-8994(88)90071-9


  • eng

Conference Location

  • United States