The dexamethasone suppression test in prepubertal depressed children.


Journal Article

The authors evaluated 18 dysphoric children aged 6--12 years by structured clinical assessments and an overnight dexamethasone suppression test (DST) administered on an outpatient basis. Nine children met diagnostic criteria for major depressive disorder, and 8 of the 9 also met the Research Diagnostic Criteria for endogenous depression. Of the 9 depressed children, 5 had abnormal DST results; 8 of the 9 nondepressed children had normal test results. The results suggest that endogenous depression in childhood is not a rare condition and that it is clinically and neuroendocrinologically similar to the adult disorder. The DST may be useful as a diagnostic aid with depressed children.

Full Text

Cited Authors

  • Poznanski, EO; Carroll, BJ; Banegas, MC; Cook, SC; Grossman, JA

Published Date

  • March 1, 1982

Published In

Volume / Issue

  • 139 / 3

Start / End Page

  • 321 - 324

PubMed ID

  • 7058946

Pubmed Central ID

  • 7058946

International Standard Serial Number (ISSN)

  • 0002-953X

Digital Object Identifier (DOI)

  • 10.1176/ajp.139.3.321


  • eng

Conference Location

  • United States