Comparison of early and delayed inpatient dexamethasone suppression tests.


Journal Article

Ninety-five inpatients completed a dexamethasone suppression test (DST) within 72 hours after admission and again after at least 1 week of medication-free hospital care. The frequency of cortisol nonsuppression in patients with endogenous depression (ED) was high and not significantly different at both tests. In patients with diagnoses other than ED, the higher rate of cortisol nonsuppression at the first DST was associated with a significant decrease in test specificity. Change in postdexamethasone cortisol levels at repeat testing was associated with a decrease in depressive symptomatology, but was not related to weight change during hospitalization.

Full Text

Cited Authors

  • Haskett, RF; Zis, AP; Albala, AA; Lohr, NE; Carroll, BJ

Published Date

  • February 1989

Published In

Volume / Issue

  • 27 / 2

Start / End Page

  • 161 - 171

PubMed ID

  • 2710864

Pubmed Central ID

  • 2710864

Electronic International Standard Serial Number (EISSN)

  • 1872-7123

International Standard Serial Number (ISSN)

  • 0165-1781

Digital Object Identifier (DOI)

  • 10.1016/0165-1781(89)90131-5


  • eng