Detailed analysis of estrous-related changes in wheel running and self-stimulation.


Journal Article

Previous studies have demonstrated that a number of behaviors change their probability of occurrence during the estrous cycle. Wheel running is known to show estrous-related changes while reports upon intracranial reinforcement (self-stimulation, ICS) have been equivocal. The present studies examined both behaviors to further resolve the underlying behavioral determinants of these estrous effects. Data for wheel running and intracranial self-stimulation behaviors of adult female Holtzman rats were collected nightly on a minute by minute basis across the estrous cycle. It was found that: (a) both behaviors showed significant estrous-related changes in frequency; (b) the two behaviors occurred in discontinuous episodes (bursts) during the dark phase of the diurnal cycle; and (c) of three burst parameters (number/session, average length, rate of response), number proved the best predictor of estrous-related behavioral change. Burst number may reflect an important motivational parameter underlying estrous-related changes in behavior.

Full Text

Cited Authors

  • Steiner, M; Katz, RJ; Carroll, BJ

Published Date

  • January 1, 1982

Published In

Volume / Issue

  • 28 / 1

Start / End Page

  • 201 - 204

PubMed ID

  • 7200615

Pubmed Central ID

  • 7200615

International Standard Serial Number (ISSN)

  • 0031-9384

Digital Object Identifier (DOI)

  • 10.1016/0031-9384(82)90127-5


  • eng

Conference Location

  • United States