Impaired lymphocyte function in depressive illness.


Journal Article

Mood states and immunity may be related. To investigate the immune status of patients with primary depressive illness, we compared in-vitro lymphocytic responses to three different mitogens in 26 drug-free depressed patients and 20 normal controls of comparable age and sex. We observed a generalized and marked decrease in the lymphocyte mitogenic activity among the depressive group. This defect in lymphocyte function may be indicative of an impairment in cell-mediated immunity in patients with primary depressive illness.

Full Text

Cited Authors

  • Kronfol, Z; Silva, J; Greden, J; Dembinski, S; Gardner, R; Carroll, B

Published Date

  • July 18, 1983

Published In

Volume / Issue

  • 33 / 3

Start / End Page

  • 241 - 247

PubMed ID

  • 6865657

Pubmed Central ID

  • 6865657

International Standard Serial Number (ISSN)

  • 0024-3205

Digital Object Identifier (DOI)

  • 10.1016/0024-3205(83)90382-x


  • eng

Conference Location

  • Netherlands