Adrenergic control of motor activity: effects of PNMT inhibition upon open field behavior in the rat.

Published

Journal Article

Two inhibitors of brain PNMT were given to rats in doses which caused equivalent reductions in enzyme activity. Each drug produced similar and dose-related decreases in ambulation, rearing and defecation during open field behavioral testing. Central adrenergic (epinephrine containing) system may be necessary for normal open field behavior. This may reflect an interaction with other monoamines, particularly dopamine.

Full Text

Pubmed Central version
Link to Item

Cited Authors

Katz, RJ; Turner, BB; Roth, K; Carroll, BJ

Published Date

October 1978

Published In

Pharmacology, Biochemistry, and Behavior

Volume / Issue

9 / 4

Start / End Page

417 - 420

PubMed ID

733828

Pubmed Central ID

733828

International Standard Serial Number (ISSN)

0091-3057

Language

Conference Location

United States