Clinical associations of 11-hydroxycorticosteroid suppression and non-suppression in severe depressive illnesses.
Published
Journal Article
Fifty patients with severe depression were separated into two groups by the responses of their plasma 11-hydroxycorticosteriod levels to a midnight dose of 2 mg. of dexamethasone. Clinical and questionary comparisons were made between the two groups of patients, who were similar as regards age, sex, and length of symptoms before admission to hospital. No differences were found between the groups of severely ill patients as regards the severity of their depression and anxiety assessed by questionary. Nevertheless, agitation was significantly greater in the patients whose corticosteroid levels were not suppressed by dexamethasone and adverse childhood experiences in those whose levels were suppressed.
Full Text
Cited Authors
- Carroll, BJ; Davies, B
Published Date
- March 28, 1970
Published In
Volume / Issue
- 1 / 5699
Start / End Page
- 789 - 791
PubMed ID
- 5443383
Pubmed Central ID
- 5443383
International Standard Serial Number (ISSN)
- 0007-1447
Digital Object Identifier (DOI)
- 10.1136/bmj.1.5699.789
Language
- eng
Conference Location
- England