Two measures of health-related quality of life in morbid obesity.


Journal Article

OBJECTIVE: To compare health-related quality of life (HRQOL) measures in obese presurgery patients with and without binge-eating disorder (BED) and to investigate the relationship between a generic [short form-36 (SF-36)] and a disease-specific HRQOL measure [Impact of Weight on Quality of Life Questionnaire (IWQOL)] and measures of eating-related and general psychopathology. RESEARCH METHODS AND PROCEDURES: One hundred ten patients ages 19 to 62 years with a mean body mass index of 48.4 +/- 8.3 kg/m(2) who were evaluated for gastric bypass surgery were asked to fill out questionnaires assessing eating-related and general psychopathology (depression, self-esteem), as well as the two HRQOL questionnaires. BED was assessed by self-report. RESULTS: Nineteen (17.3%) patients met criteria for BED. Significant differences between patients with and without BED were found for four of the eight subscales of the SF-36-with effect sizes ranging from 0.44 to 0.75-and for the total score and three of the five subscales of the IWQOL-Lite-with effect sizes from 0.57 to 0.74. The mental composite score of the SF-36 as well as the IWQOL total score correlated significantly with the measures of psychopathology. DISCUSSION: This is the first study comparing the results of HRQOL measures in morbidly obese presurgery patients with and without BED. The results indicate that BED has a profound negative impact on HRQOL that exceeds the influence of obesity. Both HRQOL measures were able to reliably discriminate between patients with and without BED. Depression and self-esteem influenced HRQOL in a similar way as binge eating.

Full Text

Duke Authors

Cited Authors

  • De Zwaan, M; Mitchell, JE; Howell, LM; Monson, N; Swan-Kremeier, L; Roerig, JL; Kolotkin, RL; Crosby, RD

Published Date

  • November 2002

Published In

Volume / Issue

  • 10 / 11

Start / End Page

  • 1143 - 1151

PubMed ID

  • 12429878

Pubmed Central ID

  • 12429878

International Standard Serial Number (ISSN)

  • 1071-7323

Digital Object Identifier (DOI)

  • 10.1038/oby.2002.155


  • eng

Conference Location

  • United States