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Impact of weight loss and regain on quality of life: mirror image or differential effect?

Publication ,  Journal Article
Engel, SG; Crosby, RD; Kolotkin, RL; Hartley, GG; Williams, GR; Wonderlich, SA; Mitchell, JE
Published in: Obes Res
October 2003

OBJECTIVE: To compare the impact of weight regain and weight loss on health-related quality of life. RESEARCH METHODS AND PROCEDURES: Subjects were 122 (106 women, 16 men) overweight and obese participants in a weight reduction program (phentermine-fenfluramine and dietary counseling) who had initially lost at least 5% of their total body weight and then regained at least 5% of their weight during the follow-up period. Follow-up periods ranged from 10 to 41 months (mean, 28 months). Participants completed the Impact of Weight on Quality of Life-Lite, an obesity-specific health-related quality of life (HRQOL) measure, at 3-month intervals. RESULTS: Mean BMI at baseline was 40.9 +/- 6.6 kg/m(2) (range, 29.2 to 63.7 kg/m(2)). Average weight loss from entry was 18.8 +/- 6.7% (range, 6.0% to 43.7%), and average regain was 10.1 +/-4.4% of baseline weight (range, 5.0% to 30.6%). The effects of weight regain on HRQOL mirrored the effects of weight loss-rates of HRQOL change were similar in magnitude but different in direction for comparable weight loss and regain. Those with more severe initial impairments in HRQOL experienced greater improvements in HRQOL during weight loss as well as greater deterioration during weight regain than those with less severe impairments. DISCUSSION: Weight loss and regain produced mirror image changes in HRQOL. The initial severity of HRQOL impairment had a greater impact on the magnitude of HRQOL change than the direction of weight change. Findings underscore the importance of maintaining weight loss for the purposes of retaining obesity-specific HRQOL benefits.

Duke Scholars

Published In

Obes Res

DOI

ISSN

1071-7323

Publication Date

October 2003

Volume

11

Issue

10

Start / End Page

1207 / 1213

Location

United States

Related Subject Headings

  • Weight Loss
  • Weight Gain
  • Quality of Life
  • Obesity
  • Models, Psychological
  • Middle Aged
  • Male
  • Longitudinal Studies
  • Linear Models
  • Interviews as Topic
 

Citation

APA
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ICMJE
MLA
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Engel, S. G., Crosby, R. D., Kolotkin, R. L., Hartley, G. G., Williams, G. R., Wonderlich, S. A., & Mitchell, J. E. (2003). Impact of weight loss and regain on quality of life: mirror image or differential effect? Obes Res, 11(10), 1207–1213. https://doi.org/10.1038/oby.2003.166
Engel, Scott G., Ross D. Crosby, Ronette L. Kolotkin, Guilford G. Hartley, G Rhys Williams, Stephen A. Wonderlich, and James E. Mitchell. “Impact of weight loss and regain on quality of life: mirror image or differential effect?Obes Res 11, no. 10 (October 2003): 1207–13. https://doi.org/10.1038/oby.2003.166.
Engel SG, Crosby RD, Kolotkin RL, Hartley GG, Williams GR, Wonderlich SA, et al. Impact of weight loss and regain on quality of life: mirror image or differential effect? Obes Res. 2003 Oct;11(10):1207–13.
Engel, Scott G., et al. “Impact of weight loss and regain on quality of life: mirror image or differential effect?Obes Res, vol. 11, no. 10, Oct. 2003, pp. 1207–13. Pubmed, doi:10.1038/oby.2003.166.
Engel SG, Crosby RD, Kolotkin RL, Hartley GG, Williams GR, Wonderlich SA, Mitchell JE. Impact of weight loss and regain on quality of life: mirror image or differential effect? Obes Res. 2003 Oct;11(10):1207–1213.

Published In

Obes Res

DOI

ISSN

1071-7323

Publication Date

October 2003

Volume

11

Issue

10

Start / End Page

1207 / 1213

Location

United States

Related Subject Headings

  • Weight Loss
  • Weight Gain
  • Quality of Life
  • Obesity
  • Models, Psychological
  • Middle Aged
  • Male
  • Longitudinal Studies
  • Linear Models
  • Interviews as Topic