An acoustofluidic sputum liquefier.
Publication
, Journal Article
Huang, P-H; Ren, L; Nama, N; Li, S; Li, P; Yao, X; Cuento, RA; Wei, C-H; Chen, Y; Xie, Y; Nawaz, AA; Alevy, YG; Holtzman, MJ; McCoy, JP ...
Published in: Lab on a chip
August 2015
We demonstrate the first microfluidic-based on-chip liquefaction device for human sputum samples. Our device is based on an acoustofluidic micromixer using oscillating sharp edges. This acoustofluidic sputum liquefier can effectively and uniformly liquefy sputum samples at a throughput of 30 μL min(-1). Cell viability and integrity are maintained during the sputum liquefaction process. Our acoustofluidic sputum liquefier can be conveniently integrated with other microfluidic units to enable automated on-chip sputum processing and analysis.
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Published In
Lab on a chip
DOI
EISSN
1473-0189
ISSN
1473-0197
Publication Date
August 2015
Volume
15
Issue
15
Start / End Page
3125 / 3131
Related Subject Headings
- Sputum
- Specimen Handling
- Sonication
- Neutrophils
- Microfluidic Analytical Techniques
- Humans
- Flow Cytometry
- Equipment Design
- Eosinophils
- Cell Survival
Citation
APA
Chicago
ICMJE
MLA
NLM
Huang, P.-H., Ren, L., Nama, N., Li, S., Li, P., Yao, X., … Huang, T. J. (2015). An acoustofluidic sputum liquefier. Lab on a Chip, 15(15), 3125–3131. https://doi.org/10.1039/c5lc00539f
Huang, Po-Hsun, Liqiang Ren, Nitesh Nama, Sixing Li, Peng Li, Xianglan Yao, Rosemarie A. Cuento, et al. “An acoustofluidic sputum liquefier.” Lab on a Chip 15, no. 15 (August 2015): 3125–31. https://doi.org/10.1039/c5lc00539f.
Huang P-H, Ren L, Nama N, Li S, Li P, Yao X, et al. An acoustofluidic sputum liquefier. Lab on a chip. 2015 Aug;15(15):3125–31.
Huang, Po-Hsun, et al. “An acoustofluidic sputum liquefier.” Lab on a Chip, vol. 15, no. 15, Aug. 2015, pp. 3125–31. Epmc, doi:10.1039/c5lc00539f.
Huang P-H, Ren L, Nama N, Li S, Li P, Yao X, Cuento RA, Wei C-H, Chen Y, Xie Y, Nawaz AA, Alevy YG, Holtzman MJ, McCoy JP, Levine SJ, Huang TJ. An acoustofluidic sputum liquefier. Lab on a chip. 2015 Aug;15(15):3125–3131.
Published In
Lab on a chip
DOI
EISSN
1473-0189
ISSN
1473-0197
Publication Date
August 2015
Volume
15
Issue
15
Start / End Page
3125 / 3131
Related Subject Headings
- Sputum
- Specimen Handling
- Sonication
- Neutrophils
- Microfluidic Analytical Techniques
- Humans
- Flow Cytometry
- Equipment Design
- Eosinophils
- Cell Survival