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Interpreting microarray results with gene ontology and MeSH

Publication ,  Journal Article
Osborne, JD; Zhu, L; Lin, SM; Kibbe, WA
Published in: Methods in Molecular Biology
March 24, 2007

Methods are described to take a list of genes generated from a microarray experiment and interpret these results using various tools and ontologies. A workflow is described that details how to convert gene identifiers with SOURCE and MatchMiner and then use these converted gene lists to search the gene ontology (GO) and the medical subject headings (MeSH) ontology. Examples of searching GO with DAVID, EASE, and GOMiner are provided along with an interpretation of results. The mining of MeSH using high-density array pattern interpreter with a set of gene identifiers is also described. © Humana Press Inc.

Duke Scholars

Published In

Methods in Molecular Biology

DOI

ISSN

1064-3745

Publication Date

March 24, 2007

Volume

377

Start / End Page

223 / 241

Related Subject Headings

  • Developmental Biology
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0601 Biochemistry and Cell Biology
  • 0399 Other Chemical Sciences
 

Citation

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Osborne, J. D., Zhu, L., Lin, S. M., & Kibbe, W. A. (2007). Interpreting microarray results with gene ontology and MeSH. Methods in Molecular Biology, 377, 223–241. https://doi.org/10.1385/1-59745-390-0:223
Osborne, J. D., L. Zhu, S. M. Lin, and W. A. Kibbe. “Interpreting microarray results with gene ontology and MeSH.” Methods in Molecular Biology 377 (March 24, 2007): 223–41. https://doi.org/10.1385/1-59745-390-0:223.
Osborne JD, Zhu L, Lin SM, Kibbe WA. Interpreting microarray results with gene ontology and MeSH. Methods in Molecular Biology. 2007 Mar 24;377:223–41.
Osborne, J. D., et al. “Interpreting microarray results with gene ontology and MeSH.” Methods in Molecular Biology, vol. 377, Mar. 2007, pp. 223–41. Scopus, doi:10.1385/1-59745-390-0:223.
Osborne JD, Zhu L, Lin SM, Kibbe WA. Interpreting microarray results with gene ontology and MeSH. Methods in Molecular Biology. 2007 Mar 24;377:223–241.

Published In

Methods in Molecular Biology

DOI

ISSN

1064-3745

Publication Date

March 24, 2007

Volume

377

Start / End Page

223 / 241

Related Subject Headings

  • Developmental Biology
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0601 Biochemistry and Cell Biology
  • 0399 Other Chemical Sciences