Autologous serum and plasma rich in growth factors in ophthalmology: preclinical and clinical studies.

Journal Article (Journal Article;Review)

The use of blood derivatives represents an alternative therapeutic approach that is gaining interest in regenerative medicine due to its potential to stimulate and accelerate tissue healing. Autologous serum eye drops and platelet-enriched plasma eye drops are being used in the treatment of different ophthalmological disorders. In this review, we summarize the different blood-derived formulations used in the treatment and care of ocular surface disorders. The biological basis and use of autologous serum and plasma rich in growth factors are deeply evaluated as well as the challenges to be addressed in the future in this new generation of blood-derived therapies.

Full Text

Duke Authors

Cited Authors

  • Anitua, E; Muruzabal, F; Tayebba, A; Riestra, A; Perez, VL; Merayo-Lloves, J; Orive, G

Published Date

  • December 2015

Published In

Volume / Issue

  • 93 / 8

Start / End Page

  • e605 - e614

PubMed ID

  • 25832910

Electronic International Standard Serial Number (EISSN)

  • 1755-3768

Digital Object Identifier (DOI)

  • 10.1111/aos.12710


  • eng

Conference Location

  • England