Ocular manifestations of ANCA-associated vasculitis.

Journal Article (Journal Article)

The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides-Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome-can present with various ophthalmic manifestations. In a subset of patients, these findings may be the earliest indicators of systemic disease. Orbital and anterior segment findings are most common, whereas posterior segment complications such as retinal vasculitis and optic neuropathy occur much less frequently. This article describes the distinguishing features of associated ophthalmic disease, focusing on the manifestations clinicians are most likely to encounter and those with the most significant ocular morbidity. Although the ANCA-associated vasculitides require systemic workup and treatment, this article discusses diagnostic and therapeutic modalities often used concurrently for ophthalmic disease.

Full Text

Duke Authors

Cited Authors

  • Kubal, AA; Perez, VL

Published Date

  • August 2010

Published In

Volume / Issue

  • 36 / 3

Start / End Page

  • 573 - 586

PubMed ID

  • 20688251

Electronic International Standard Serial Number (EISSN)

  • 1558-3163

Digital Object Identifier (DOI)

  • 10.1016/j.rdc.2010.05.005


  • eng

Conference Location

  • United States