An evaluation of metrics for assessing maternal exposure to agricultural pesticides.


Journal Article

We evaluate the use of three different exposure metrics to estimate maternal agricultural pesticide exposure during pregnancy. Using a geographic information system-based method of pesticide exposure estimation, we combine data on crop density and specific pesticide application amounts/dates to create the three exposure metrics. For illustration purposes, we create each metric for a North Carolina cohort of pregnant women, 2003-2005, and analyze the risk of congenital anomaly development with a focus on metric comparisons. Based on the results, and the need to balance data collection efforts/computational efficiency with accuracy, the metric which estimates total chemical exposure using application dates based on crop-specific earliest planting and latest harvesting information is preferred. Benefits and drawbacks of each metric are discussed and recommendations for extending the analysis to other states are provided.

Full Text

Cited Authors

  • Warren, JL; Luben, TJ; Sanders, AP; Brownstein, NC; Herring, AH; Meyer, RE

Published Date

  • September 2014

Published In

Volume / Issue

  • 24 / 5

Start / End Page

  • 497 - 503

PubMed ID

  • 24149974

Pubmed Central ID

  • 24149974

Electronic International Standard Serial Number (EISSN)

  • 1559-064X

International Standard Serial Number (ISSN)

  • 1559-0631

Digital Object Identifier (DOI)

  • 10.1038/jes.2013.75


  • eng