Second trimester folate status and preterm birth.
The purpose of this study was to show that maternal folate status during pregnancy may be related to preterm birth.
Women were recruited at 24 to 29 weeks' gestation from 1995 to 2000 into the Pregnancy, Infection, and Nutrition Study. Those who completed an interview and a food frequency questionnaire, or provided a blood sample for radioassay of serum (n = 2026) and red blood cell (n = 1034) folate were included.
Mean daily dietary folate intake was 463 microg (SD +/- 248). Intake ConclusionThese results support the hypothesis that low folate levels during the second trimester of pregnancy are associated with an increased risk of preterm birth.
Siega-Riz, AM; Savitz, DA; Zeisel, SH; Thorp, JM; Herring, A
Volume / Issue
Start / End Page
Electronic International Standard Serial Number (EISSN)
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)