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Programmable assembly of pressure sensors using pattern-forming bacteria.

Publication ,  Journal Article
Cao, Y; Feng, Y; Ryser, MD; Zhu, K; Herschlag, G; Cao, C; Marusak, K; Zauscher, S; You, L
Published in: Nat Biotechnol
November 2017

Biological systems can generate microstructured materials that combine organic and inorganic components and possess diverse physical and chemical properties. However, these natural processes in materials fabrication are not readily programmable. Here, we use a synthetic-biology approach to assemble patterned materials. We demonstrate programmable fabrication of three-dimensional (3D) materials by printing engineered self-patterning bacteria on permeable membranes that serve as a structural scaffold. Application of gold nanoparticles to the colonies creates hybrid organic-inorganic dome structures. The dynamics of the dome structures' response to pressure is determined by their geometry (colony size, dome height, and pattern), which is easily modified by varying the properties of the membrane (e.g., pore size and hydrophobicity). We generate resettable pressure sensors that process signals in response to varying pressure intensity and duration.

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Published In

Nat Biotechnol

DOI

EISSN

1546-1696

Publication Date

November 2017

Volume

35

Issue

11

Start / End Page

1087 / 1093

Location

United States

Related Subject Headings

  • Pressure
  • Metal Nanoparticles
  • Gold
  • Escherichia coli
  • Biosensing Techniques
 

Citation

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Cao, Y., Feng, Y., Ryser, M. D., Zhu, K., Herschlag, G., Cao, C., … You, L. (2017). Programmable assembly of pressure sensors using pattern-forming bacteria. Nat Biotechnol, 35(11), 1087–1093. https://doi.org/10.1038/nbt.3978
Cao, Yangxiaolu, Yaying Feng, Marc D. Ryser, Kui Zhu, Gregory Herschlag, Changyong Cao, Katherine Marusak, Stefan Zauscher, and Lingchong You. “Programmable assembly of pressure sensors using pattern-forming bacteria.Nat Biotechnol 35, no. 11 (November 2017): 1087–93. https://doi.org/10.1038/nbt.3978.
Cao Y, Feng Y, Ryser MD, Zhu K, Herschlag G, Cao C, et al. Programmable assembly of pressure sensors using pattern-forming bacteria. Nat Biotechnol. 2017 Nov;35(11):1087–93.
Cao, Yangxiaolu, et al. “Programmable assembly of pressure sensors using pattern-forming bacteria.Nat Biotechnol, vol. 35, no. 11, Nov. 2017, pp. 1087–93. Pubmed, doi:10.1038/nbt.3978.
Cao Y, Feng Y, Ryser MD, Zhu K, Herschlag G, Cao C, Marusak K, Zauscher S, You L. Programmable assembly of pressure sensors using pattern-forming bacteria. Nat Biotechnol. 2017 Nov;35(11):1087–1093.

Published In

Nat Biotechnol

DOI

EISSN

1546-1696

Publication Date

November 2017

Volume

35

Issue

11

Start / End Page

1087 / 1093

Location

United States

Related Subject Headings

  • Pressure
  • Metal Nanoparticles
  • Gold
  • Escherichia coli
  • Biosensing Techniques