Nutrition Therapy in Sepsis.

Journal Article (Journal Article;Review)

Sepsis is characterized by early massive catabolism, lean body mass (LBM) loss, and escalating hypermetabolism persisting for months to years. Early enteral nutrition should attempt to correct micronutrient/vitamin deficiencies, deliver adequate protein and moderated nonprotein calories, as well-nourished patients can generate reasonable endogenous energy. After resuscitation, increasing protein/calories are needed to attenuate LBM loss and promote recovery. Malnutrition screening is essential, and parenteral nutrition can be safely added when enteral nutrition is failing based on preillness malnutrition. Following discharge from intensive care unit, significantly increased protein/calorie delivery is required for months to years to facilitate functional and LBM recovery.

Full Text

Duke Authors

Cited Authors

  • Wischmeyer, PE

Published Date

  • January 2018

Published In

Volume / Issue

  • 34 / 1

Start / End Page

  • 107 - 125

PubMed ID

  • 29149933

Pubmed Central ID

  • PMC6447319

Electronic International Standard Serial Number (EISSN)

  • 1557-8232

Digital Object Identifier (DOI)

  • 10.1016/j.ccc.2017.08.008


  • eng

Conference Location

  • United States