Objective outcome measures: Collecting meaningful data on alopecia areata.
BACKGROUND: Although alopecia areata is a common disorder, it has no US Food and Drug Administration-approved treatment and evidence-based therapeutic data are lacking. OBJECTIVE: To develop guidelines for the diagnosis, evaluation, assessment, response criteria, and end points for alopecia areata. METHODS: Literature review and expert opinion of a group of dermatologists specializing in hair disorders. RESULTS: Standardized methods of assessing and tracking hair loss and growth, including new scoring techniques, response criteria, and end points in alopecia areata are presented. LIMITATIONS: The additional time to perform the assessments is the primary limitation to use of the methodology in clinical practice. CONCLUSION: Use of these measures will facilitate collection of standardized outcome data on therapeutic agents used in alopecia areata both in clinical practice and in clinical trials.
Olsen, EA; Roberts, J; Sperling, L; Tosti, A; Shapiro, J; McMichael, A; Bergfeld, W; Callender, V; Mirmirani, P; Washenik, K; Whiting, D; Cotsarelis, G; Hordinsky, M
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