Objective outcome measures: Collecting meaningful data on alopecia areata.

Journal Article (Journal Article;Review)

BACKGROUND: Although alopecia areata is a common disorder, it has no US Food and Drug Administration-approved treatment and evidence-based therapeutic data are lacking. OBJECTIVE: To develop guidelines for the diagnosis, evaluation, assessment, response criteria, and end points for alopecia areata. METHODS: Literature review and expert opinion of a group of dermatologists specializing in hair disorders. RESULTS: Standardized methods of assessing and tracking hair loss and growth, including new scoring techniques, response criteria, and end points in alopecia areata are presented. LIMITATIONS: The additional time to perform the assessments is the primary limitation to use of the methodology in clinical practice. CONCLUSION: Use of these measures will facilitate collection of standardized outcome data on therapeutic agents used in alopecia areata both in clinical practice and in clinical trials.

Full Text

Duke Authors

Cited Authors

  • Olsen, EA; Roberts, J; Sperling, L; Tosti, A; Shapiro, J; McMichael, A; Bergfeld, W; Callender, V; Mirmirani, P; Washenik, K; Whiting, D; Cotsarelis, G; Hordinsky, M

Published Date

  • September 2018

Published In

Volume / Issue

  • 79 / 3

Start / End Page

  • 470 - 478.e3

PubMed ID

  • 29128463

Pubmed Central ID

  • PMC7450487

Electronic International Standard Serial Number (EISSN)

  • 1097-6787

Digital Object Identifier (DOI)

  • 10.1016/j.jaad.2017.10.048


  • eng

Conference Location

  • United States