Anatomy and Breast Cancer Staging: Is It Still Relevant?

Journal Article (Journal Article;Review)

Breast cancer staging concisely summarizes disease status, creating a framework for assessing and relaying prognostic information. The fundamental concepts and components of breast cancer staging are reviewed. The AJCC Cancer Staging Manual, which includes traditional anatomic factors, now includes additional tumor characteristics: tumor grade, estrogen receptor status, progesterone receptor status, human epidermal growth factor receptor 2 status, and (when available) multigene panel testing from the primary tumor. With these updates, staging provides the most reliable system for accurately predicting patient outcome. When the AJCC 8th edition guidelines are adopted, they will more closely reflect tumor biology.

Full Text

Duke Authors

Cited Authors

  • Plichta, JK; Campbell, BM; Mittendorf, EA; Hwang, ES

Published Date

  • January 2018

Published In

Volume / Issue

  • 27 / 1

Start / End Page

  • 51 - 67

PubMed ID

  • 29132565

Electronic International Standard Serial Number (EISSN)

  • 1558-5042

Digital Object Identifier (DOI)

  • 10.1016/j.soc.2017.07.010


  • eng

Conference Location

  • United States