A longitudinal molecular surveillance study of human polyomavirus viremia in heart, kidney, liver, and pancreas transplant patients.

Journal Article (Journal Article)

In this study of 263 heart, kidney, liver, and pancreas transplant patients, BK virus (BKV) and JC virus (JCV) DNAemia were observed most commonly in kidney and/or pancreas transplant patients (26%), although they were also observed, to a lesser extent, in heart (7%) and liver (4%) transplant patients. The majority of episodes of polyomavirus DNAemia were subclinical, although, in some cases, BKV DNAemia was associated with kidney rejection, and JCV DNAemia was accompanied by nonspecific symptoms. Hence, BKV and JCV DNAemia are not uncommon during the first year after kidney, heart, liver, and pancreas transplantation, and they could be associated with certain clinical syndromes in transplant patients.

Full Text

Duke Authors

Cited Authors

  • Razonable, RR; Brown, RA; Humar, A; Covington, E; Alecock, E; Paya, CV; PV16000 Study Group,

Published Date

  • October 15, 2005

Published In

Volume / Issue

  • 192 / 8

Start / End Page

  • 1349 - 1354

PubMed ID

  • 16170751

International Standard Serial Number (ISSN)

  • 0022-1899

Digital Object Identifier (DOI)

  • 10.1086/466532


  • eng

Conference Location

  • United States