A novel role for renal epithelial cells and the medullary sodium gradient in the local immune response.
Published
Journal Article
The extreme hypertonicity of the renal medulla plays a central role in regulating volume status. A recent publication in Cell has identified a novel role for the high sodium environment and the local epithelial cells in the recruitment of mononuclear phagocytes, potentially contributing to the defense against ascending urinary tract infection.
Full Text
Duke Authors
Cited Authors
- Wyatt, CM; Crowley, SD
Published Date
- December 2017
Published In
Volume / Issue
- 92 / 6
Start / End Page
- 1308 - 1311
PubMed ID
- 29153132
Pubmed Central ID
- 29153132
Electronic International Standard Serial Number (EISSN)
- 1523-1755
Digital Object Identifier (DOI)
- 10.1016/j.kint.2017.10.005
Language
- eng
Conference Location
- United States