The reaction of methionine with hydroxyl radical: reactive intermediates and methanethiol production.


Journal Article

The mechanisms of reaction of methionine with hydroxyl radical are not fully understood. Here, we unequivocally show using electron paramagnetic resonance spin-trapping spectroscopy and GC-FID and GC-MS, the presence of specific carbon-, nitrogen- and sulfur-centered radicals as intermediates of this reaction, as well as the liberation of methanethiol as a gaseous end product. Taking into account the many roles that methionine has in eco- and biosystems, our results may elucidate redox chemistry of this amino acid and processes that methionine is involved in.

Full Text

Cited Authors

  • Spasojević, I; Bogdanović Pristov, J; Vujisić, L; Spasić, M

Published Date

  • June 2012

Published In

Volume / Issue

  • 42 / 6

Start / End Page

  • 2439 - 2445

PubMed ID

  • 21830117

Pubmed Central ID

  • 21830117

Electronic International Standard Serial Number (EISSN)

  • 1438-2199

International Standard Serial Number (ISSN)

  • 0939-4451

Digital Object Identifier (DOI)

  • 10.1007/s00726-011-1049-1


  • eng