Primary granulocytic sarcoma of larynx.

Journal Article (Journal Article;Review)

BACKGROUND: Granulocytic sarcoma is an extramedullary tumor of myeloblasts. The purpose of this report was to present a case of a primary laryngeal granulocytic sarcoma and review of the literature. METHODS: A literature review was performed using Medline and PubMed databases to search for cases of all primary and secondary myelogenous tumors of the larynx. RESULTS: A 36-year-old man presented with a mass involving the preepiglottic space that was histologically confirmed as an extramedullary acute myeloid leukemia, or granulocytic sarcoma. Our review found 18 cases of secondary involvement of the larynx by myelogenous tumors, and only 1 previously reported case of primary laryngeal granulocytic sarcoma. CONCLUSION: The detection of granulocytic sarcoma is difficult given its rarity and nonspecific presentation. To our knowledge, this is the second reported case of primary granulocytic sarcoma of the larynx reported in the literature.

Full Text

Duke Authors

Cited Authors

  • Kim, LY; Purkey, MT; Patel, MR; Ghosh, A; Hartner, L; Newman, JG

Published Date

  • March 2015

Published In

Volume / Issue

  • 37 / 3

Start / End Page

  • E38 - E44

PubMed ID

  • 24953995

Electronic International Standard Serial Number (EISSN)

  • 1097-0347

Digital Object Identifier (DOI)

  • 10.1002/hed.23805


  • eng

Conference Location

  • United States