Global risk of coronary heart disease: assessment and application.

Published

Journal Article (Review)

Coronary heart disease is the most common cause of death in the United States. The conventional risk factor approach to primary prevention excludes many patients who could benefit from preventive therapies. A global risk approach allows more accurate estimates of risk to guide clinical primary prevention efforts. Global risk of coronary heart disease is a calculation of the absolute risk of having a coronary heart disease event (e.g., death, myocardial infarction) over a specified period. It is based on an empiric equation that combines major risk factors, such as blood pressure and cholesterol levels. When physicians know a patient's global risk of coronary heart disease, they are more likely to prescribe risk-reducing therapies such as antihypertensives, statins, and aspirin. In addition, patients who know their risk level are more likely to initiate risk-reducing therapies. Many tools are available to estimate global risk, including several Web-based calculators. In the United States, tools based on the Framingham Heart Study are recommended.

Full Text

Duke Authors

Cited Authors

  • Viera, AJ; Sheridan, SL

Published Date

  • August 2010

Published In

Volume / Issue

  • 82 / 3

Start / End Page

  • 265 - 274

PubMed ID

  • 20672791

Pubmed Central ID

  • 20672791

Electronic International Standard Serial Number (EISSN)

  • 1532-0650

International Standard Serial Number (ISSN)

  • 0002-838X

Language

  • eng