Distinct medial temporal lobe network states as neural contexts for motivated memory formation


Book Section

© Springer International Publishing AG 2017. In this chapter we examine how motivation creates a neural context for learning by dynamically engaging medial temporal lobe (MTL) systems. We review findings demonstrating that distinct modulatory networks, centered on the ventral tegmental area (VTA) and amygdala, are coherently recruited during specific motivational states and shunt encoding to hippocampal versus cortical MTL systems during learning. We posit that these shifts in encoding substrate serve to tailor both the content and form of memory representations, and speculate that these different representations support current and future adaptive behavior.

Full Text

Duke Authors

Cited Authors

  • Murty, VP; Adcock, RA

Published Date

  • January 1, 2017

Book Title

  • The Hippocampus from Cells to Systems: Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition

Start / End Page

  • 467 - 501

International Standard Book Number 13 (ISBN-13)

  • 9783319504056

Digital Object Identifier (DOI)

  • 10.1007/978-3-319-50406-3_15

Citation Source

  • Scopus