[Oncolytic viral therapy of gliomas: review of the literature].


Journal Article (Review)

Gliomas are the most frequent primary tumors of the brain. The standard treatment includes surgery, radiotherapy and chemotherapy, but the outcomes of patients with these tumors have remained nearly unchanged for past years. Hopefully, recent advances in molecular biology are rising new clinical expectation for patients with brain tumors. Among the novel techniques in this new field of research a new field of research, the use of oncolytic viruses has been explored in different trials during last years. In the present review we analyze the advances in the understanding of the oncolytic viral therapy of gliomas.

Full Text

Duke Authors

Cited Authors

  • Arrese, I; González, P; Miranda, P; Pérez-Núñez, A; Pascual, B; Lobato, RD

Published Date

  • April 2005

Published In

Volume / Issue

  • 16 / 2

Start / End Page

  • 158 - 168

PubMed ID

  • 15915305

Pubmed Central ID

  • 15915305

International Standard Serial Number (ISSN)

  • 1130-1473

Digital Object Identifier (DOI)

  • 10.1016/s1130-1473(05)70421-8


  • spa

Conference Location

  • Spain