Evaluation of Criteria to Detect Masked Hypertension.

Journal Article (Journal Article)

The prevalence of masked hypertension (out-of-clinic daytime systolic/diastolic blood pressure (SBP/DBP) ≥135/85 mm Hg on ambulatory blood pressure monitoring [ABPM] among adults with clinic SBP/DBP <140/90 mm Hg) is high. It is unclear who should be screened for masked hypertension. The authors derived a clinic blood pressure (CBP) index to identify populations for masked hypertension screening. Index cut points corresponding to 75% to 99% sensitivity and prehypertension were evaluated as ABPM testing criterion. In a derivation cohort (n=695), the index was clinic SBP+1.3*clinic DBP. In an external validation cohort (n=675), the sensitivity for masked hypertension using an index ≥190 mm Hg and ≥217 mm Hg and prehypertension status was 98.5%, 71.5%, and 82.5%, respectively. Using National Health and Nutrition Examination Survey data (n=11,778), the authors estimated that these thresholds would refer 118.6, 44.4, and 59.3 million US adults, respectively, to ABPM screening for masked hypertension. In conclusion, the CBP index provides a useful approach to identify candidates for masked hypertension screening using ABPM.

Full Text

Duke Authors

Cited Authors

  • Booth, JN; Muntner, P; Diaz, KM; Viera, AJ; Bello, NA; Schwartz, JE; Shimbo, D

Published Date

  • November 2016

Published In

Volume / Issue

  • 18 / 11

Start / End Page

  • 1086 - 1094

PubMed ID

  • 27126770

Pubmed Central ID

  • PMC5086321

Electronic International Standard Serial Number (EISSN)

  • 1751-7176

Digital Object Identifier (DOI)

  • 10.1111/jch.12830


  • eng

Conference Location

  • United States