West African crystalline maculopathy.

Published

Journal Article

OBJECTIVE: To report new observations in West African crystalline maculopathy. DESIGN: Retrospective, observational case series. PARTICIPANTS: Three patients drawn from a private retina practice. METHODS: Review of clinical charts and photographic studies. MAIN OUTCOME MEASURES: Distribution of intraretinal crystals and changes after laser photocoagulation, and history of ingesting foods typical in a West African diet but atypical for an American diet. RESULTS: All patients were older than 50 years, had diabetic retinopathy, ate green vegetables not found in American diets, and showed no deleterious effects of the crystals. Kola nut ingestion in 2 patients was remote and sparse, and was unknown in a third patient. The first 2 affected patients originating outside the Ibo tribe of Nigeria are reported. The pattern of retinal crystals can be changed, and the quantity of crystals reduced, by laser photocoagulation of associated diabetic retinopathy. CONCLUSIONS: West African crystalline retinopathy is distinguishable from other causes of crystalline retinopathy. It may reflect a component of the West African diet, seems to have diabetic retinopathy as a promoting factor via breakdown of the blood-retina barrier, and can be modified by laser photocoagulation of diabetic retinopathy. Increased awareness of the condition will allow physicians seeing West African immigrants to make the diagnosis and treat the patients appropriately.

Full Text

Duke Authors

Cited Authors

  • Browning, DJ

Published Date

  • May 2004

Published In

Volume / Issue

  • 111 / 5

Start / End Page

  • 921 - 925

PubMed ID

  • 15121369

Pubmed Central ID

  • 15121369

International Standard Serial Number (ISSN)

  • 0161-6420

Digital Object Identifier (DOI)

  • 10.1016/j.ophtha.2003.09.030

Language

  • eng

Conference Location

  • United States