Interobserver variability in optical coherence tomography for macular edema.


Journal Article

PURPOSE: To assess the interobserver variability of optical coherence tomography (OCT) measurements in patients with macular edema. DESIGN: Noninterventional case series using a diagnostic instrument. METHODS: Ordinary least products analysis of OCT data obtained by two masked observers from a set of 20 eyes from 10 patients. SETTING: Private retina practice. RESULTS: Foveal zone thickness measurements were operator dependent. Fixed and proportional bias was found between the two observers. Total macular volume measurements were independent of observers. CONCLUSION: Foveal zone thickness measurements are not directly comparable across different observers, but total macular volume measurements are directly comparable. Multicenter studies involving OCT measurements and clinical users of OCT data will need to factor interobserver variability into conclusions drawn from pooled OCT foveal zone thickness measurements.

Full Text

Duke Authors

Cited Authors

  • Browning, DJ

Published Date

  • June 2004

Published In

Volume / Issue

  • 137 / 6

Start / End Page

  • 1116 - 1117

PubMed ID

  • 15183798

Pubmed Central ID

  • 15183798

International Standard Serial Number (ISSN)

  • 0002-9394

Digital Object Identifier (DOI)

  • 10.1016/j.ajo.2003.12.013


  • eng

Conference Location

  • United States