Interobserver variability in optical coherence tomography for macular edema.
PURPOSE: To assess the interobserver variability of optical coherence tomography (OCT) measurements in patients with macular edema. DESIGN: Noninterventional case series using a diagnostic instrument. METHODS: Ordinary least products analysis of OCT data obtained by two masked observers from a set of 20 eyes from 10 patients. SETTING: Private retina practice. RESULTS: Foveal zone thickness measurements were operator dependent. Fixed and proportional bias was found between the two observers. Total macular volume measurements were independent of observers. CONCLUSION: Foveal zone thickness measurements are not directly comparable across different observers, but total macular volume measurements are directly comparable. Multicenter studies involving OCT measurements and clinical users of OCT data will need to factor interobserver variability into conclusions drawn from pooled OCT foveal zone thickness measurements.
Duke Scholars
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Related Subject Headings
- Tomography, Optical Coherence
- Reproducibility of Results
- Photography
- Ophthalmology & Optometry
- Observer Variation
- Macular Edema
- Humans
- 1117 Public Health and Health Services
- 1113 Opthalmology and Optometry
- 1103 Clinical Sciences
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Tomography, Optical Coherence
- Reproducibility of Results
- Photography
- Ophthalmology & Optometry
- Observer Variation
- Macular Edema
- Humans
- 1117 Public Health and Health Services
- 1113 Opthalmology and Optometry
- 1103 Clinical Sciences