Parametric yield estimation is one of the most critical-yet-challenging tasks for designing and verifying nanoscale analog and mixed-signal circuits. In this paper, we propose a novel Bayesian model fusion (BMF) technique for efficient parametric yield estimation. Our key idea is to borrow the simulation data from an early stage (e.g., schematic-level simulation) to efficiently estimate the performance distributions at a late stage (e.g., post-layout simulation). BMF statistically models the correlation between early-stage and late-stage performance distributions by Bayesian inference. In addition, a convex optimization is formulated to solve the unknown late-stage performance distributions both accurately and robustly. Several circuit examples designed in a commercial 32 nm CMOS process demonstrate that the proposed BMF technique achieves up to 3.75× runtime speedup over the traditional kernel estimation method. © 2012 ACM.