Intrauterine fetal diagnosis for hematologic and other congenital disorders.


Journal Article (Review)

Advances in prenatal diagnostic techniques allow for earlier, more rapid, and more effective detection of congenital disorders. The indications, diagnostic accuracy, and risks for invasive diagnostic techniques including amniocentesis, chorionic villus sampling, and fetal blood sampling are reviewed. Recent advances in non-invasive detection methods, such as fetal ultrasound and the isolation of fetal cells in the maternal circulation are discussed. Additionally, the intrauterine diagnosis of congenital infections and chromosomal and Mendelian disorders, as well as hematologic disorders are summarized.

Full Text

Duke Authors

Cited Authors

  • Kramer, K; Cohen, HJ

Published Date

  • March 1999

Published In

Volume / Issue

  • 19 / 1

Start / End Page

  • 239 - viii

PubMed ID

  • 10403082

Pubmed Central ID

  • 10403082

Electronic International Standard Serial Number (EISSN)

  • 1557-9832

International Standard Serial Number (ISSN)

  • 0272-2712


  • eng