The distinct roles of insulin signaling in polyphenic development.

Journal Article (Review;Journal Article)

Many insects have the ability to develop alternative morphologies in response to specific environmental signals such as photoperiod, temperature, nutrition and crowding. These signals are integrated by the brain and result in alternative patterns of secretion of developmental hormones like ecdysone, juvenile hormone and insulin-like growth factors, which, in turn, direct alternative developmental trajectories. Insulin signaling appears to be particularly important when the polyphenism involves differences in the sizes of the body, appendages and other structures, such as wings, mandibles and horns. Here we review recent advances in understanding the role of insulin signaling, and its interaction with other hormones, in the development of polyphenisms.

Full Text

Duke Authors

Cited Authors

  • Nijhout, HF; McKenna, KZ

Published Date

  • February 2018

Published In

Volume / Issue

  • 25 /

Start / End Page

  • 58 - 64

PubMed ID

  • 29602363

Electronic International Standard Serial Number (EISSN)

  • 2214-5753

International Standard Serial Number (ISSN)

  • 2214-5745

Digital Object Identifier (DOI)

  • 10.1016/j.cois.2017.11.011

Language

  • eng