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Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension in an adult Pakistani Pathan population.

Publication ,  Journal Article
Khawaja, MR; Taj, F; Ahmad, U; Saleheen, D; Jafar, T; Frossard, PM
Published in: International journal of cardiology
March 2007

This retrospective, case-control study was carried out to find putative correlations of eNOS G894T polymorphism with essential hypertension (EHT) amongst adult Pakistani Pathans. We investigated a sample population of 332 (154 men, 178 women) comprising groups of 146 hypertensives (HTs) and 186 normotensives (NTs) by assays based on polymerase chain reaction followed by restriction endonuclease analysis. The distribution of the genotypes or alleles was not statistically different in hypertensive and normotensive groups. In conclusion, the present study in a population of Pakistani adult Pathans does not support the association of the eNOS gene G894T polymorphism to essential hypertension.

Duke Scholars

Published In

International journal of cardiology

DOI

EISSN

1874-1754

ISSN

0167-5273

Publication Date

March 2007

Volume

116

Issue

1

Start / End Page

113 / 115

Related Subject Headings

  • Sex Distribution
  • Retrospective Studies
  • Polymorphism, Genetic
  • Pakistan
  • Nitric Oxide Synthase Type III
  • Middle Aged
  • Male
  • Hypertension
  • Humans
  • Genotype
 

Citation

APA
Chicago
ICMJE
MLA
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Khawaja, M. R., Taj, F., Ahmad, U., Saleheen, D., Jafar, T., & Frossard, P. M. (2007). Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension in an adult Pakistani Pathan population. International Journal of Cardiology, 116(1), 113–115. https://doi.org/10.1016/j.ijcard.2006.04.019
Khawaja, Muhammad Rizwanulhaq, Fawad Taj, Usman Ahmad, Danish Saleheen, Tazeen Jafar, and Philippe M. Frossard. “Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension in an adult Pakistani Pathan population.International Journal of Cardiology 116, no. 1 (March 2007): 113–15. https://doi.org/10.1016/j.ijcard.2006.04.019.
Khawaja MR, Taj F, Ahmad U, Saleheen D, Jafar T, Frossard PM. Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension in an adult Pakistani Pathan population. International journal of cardiology. 2007 Mar;116(1):113–5.
Khawaja, Muhammad Rizwanulhaq, et al. “Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension in an adult Pakistani Pathan population.International Journal of Cardiology, vol. 116, no. 1, Mar. 2007, pp. 113–15. Epmc, doi:10.1016/j.ijcard.2006.04.019.
Khawaja MR, Taj F, Ahmad U, Saleheen D, Jafar T, Frossard PM. Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension in an adult Pakistani Pathan population. International journal of cardiology. 2007 Mar;116(1):113–115.
Journal cover image

Published In

International journal of cardiology

DOI

EISSN

1874-1754

ISSN

0167-5273

Publication Date

March 2007

Volume

116

Issue

1

Start / End Page

113 / 115

Related Subject Headings

  • Sex Distribution
  • Retrospective Studies
  • Polymorphism, Genetic
  • Pakistan
  • Nitric Oxide Synthase Type III
  • Middle Aged
  • Male
  • Hypertension
  • Humans
  • Genotype