Urinary excretion of biopterin and neopterin in psychiatric disorders.
Journal Article (Journal Article)
Levels of urinary neopterin and biopterin were determined in patients having a diagnosis of schizophrenia, unipolar depression, or bipolar depression. Both neopterin and biopterin levels were significantly higher in the urine of patients with unipolar depression than in the urine of the control group. Subclassification of patients into primary and secondary depression demonstrated a significant elevation of urinary biopterin in both groups, whereas urinary neopterin was elevated only in those patients with primary depression. In patients with bipolar depression, neopterin excretion was elevated, but biopterin excretion did not differ from controls. No significant differences were found in schizophrenic patients.
Full Text
Duke Authors
Cited Authors
- Duch, DS; Woolf, JH; Nichol, CA; Davidson, JR; Garbutt, JC
Published Date
- February 1, 1984
Published In
Volume / Issue
- 11 / 2
Start / End Page
- 83 - 89
PubMed ID
- 6584938
International Standard Serial Number (ISSN)
- 0165-1781
Digital Object Identifier (DOI)
- 10.1016/0165-1781(84)90090-8
Language
- eng
Conference Location
- Ireland