Urinary excretion of biopterin and neopterin in psychiatric disorders.

Journal Article (Journal Article)

Levels of urinary neopterin and biopterin were determined in patients having a diagnosis of schizophrenia, unipolar depression, or bipolar depression. Both neopterin and biopterin levels were significantly higher in the urine of patients with unipolar depression than in the urine of the control group. Subclassification of patients into primary and secondary depression demonstrated a significant elevation of urinary biopterin in both groups, whereas urinary neopterin was elevated only in those patients with primary depression. In patients with bipolar depression, neopterin excretion was elevated, but biopterin excretion did not differ from controls. No significant differences were found in schizophrenic patients.

Full Text

Duke Authors

Cited Authors

  • Duch, DS; Woolf, JH; Nichol, CA; Davidson, JR; Garbutt, JC

Published Date

  • February 1, 1984

Published In

Volume / Issue

  • 11 / 2

Start / End Page

  • 83 - 89

PubMed ID

  • 6584938

International Standard Serial Number (ISSN)

  • 0165-1781

Digital Object Identifier (DOI)

  • 10.1016/0165-1781(84)90090-8


  • eng

Conference Location

  • Ireland