Biological and experimental factors affecting the assessment of cervical softening during pregnancy with shear wave elasticity imaging

Published

Conference Paper

© 2017 IEEE. Spontaneous preterm birth, the foremost source of neonatal mortality, could potentially be prevented by objectively detecting abnormal changes in the uterine cervix. Shear Wave Elasticity Imaging (SWEI) biomarkers can quantify cervical softening that precedes vaginal delivery. This task can be complicated by biological (i.e., heterogeneity of cervical stiffness and pregnancy history) and experimental confounders (i.e., posture during scanning). Here we investigate how these confounders influence shear wave speed (SWS) as an objective biomarker of cervical softening during pregnancy. We apply SWEI longitudinally in pregnant Rhesus macaques and compare SWS estimates from supine transabdominal (TA) and prone inter-cavitary (IC) approaches.

Full Text

Duke Authors

Cited Authors

  • Rosado-Mendez, IM; Drehfal, LC; Santoso, AP; Guerrero, QW; Woo, KM; Palmeri, ML; Feltovich, H; Hall, TJ

Published Date

  • October 31, 2017

Published In

Electronic International Standard Serial Number (EISSN)

  • 1948-5727

International Standard Serial Number (ISSN)

  • 1948-5719

International Standard Book Number 13 (ISBN-13)

  • 9781538633830

Digital Object Identifier (DOI)

  • 10.1109/ULTSYM.2017.8092987

Citation Source

  • Scopus