Laparoscopic cholecystectomy during pregnancy: A systematic review of 590 patients.


Journal Article (Review)

BACKGROUND:The incidence of symptomatic biliary disease during pregnancy ranges from 0.05 to 8%. Cholecystectomy is one of the common operations performed during pregnancy and laparoscopic approach has gained popularity as an attractive alternative to open surgery. METHODS:In order to evaluate the safety, feasibility, outcomes and technical aspects of laparoscopic cholecystectomy during pregnancy a comprehensive search of Medline and Cohrane Library databases was conducted. RESULTS:Fifty-one studies were deemed eligible, in which laparoscopic cholecystectomy was attempted in 590 patients. The majority of the procedures (70.7%) were performed during the second trimester. Intraoperative and postoperative complications were observed in 3.5% and 4% of the study population. Conversion rate to open surgery was 2.2%. Fetal loss rate and preterm delivery rate were 0.4% and 5.7% respectively. CONCLUSION:Laparoscopic cholecystectomy seems to be a safe alternative to open surgery during pregnancy.

Full Text

Duke Authors

Cited Authors

  • Nasioudis, D; Tsilimigras, D; Economopoulos, KP

Published Date

  • March 2016

Published In

Volume / Issue

  • 27 /

Start / End Page

  • 165 - 175

PubMed ID

  • 26826612

Pubmed Central ID

  • 26826612

Electronic International Standard Serial Number (EISSN)

  • 1743-9159

International Standard Serial Number (ISSN)

  • 1743-9191

Digital Object Identifier (DOI)

  • 10.1016/j.ijsu.2016.01.070


  • eng