Proof-of-concept study of an at-home, engaging, digital intervention for pediatric ADHD.

Journal Article (Journal Article)

OBJECTIVE: Pharmacological and behavioral therapies have limited impact on the distinct neurocognitive impairments associated with ADHD, and existing cognitive training programs have shown limited efficacy. This proof-of-concept study assessed treatment acceptability and explored outcomes for a novel digital treatment targeting cognitive processes implicated in ADHD. METHOD: Participants included 40 children with ADHD and 40 children without ADHD. Following psychiatric screening, ADHD ratings, and baseline neuropsychological measures, participants completed 28-days of at-home treatment. Neuropsychological assessment was repeated at end-of-study along with treatment satisfaction measures. RESULTS: Eighty-four percent of treatment sessions were completed and ratings showed strong intervention appeal. Significant improvements were observed on a computerized attention task for the ADHD group and a highly impaired ADHD High Severity subgroup. There was no change for the non-ADHD group. Spatial working memory also improved for the ADHD group and the ADHD High Severity subgroup. CONCLUSION: Findings provide preliminary support that this treatment may improve attention, working memory, and inhibition in children with ADHD. Future research requires larger-scale randomized controlled trials that also evaluate treatment impact on functional impairments. TRIAL REGISTRATION: NCT01943539.

Full Text

Duke Authors

Cited Authors

  • Davis, NO; Bower, J; Kollins, SH

Published Date

  • 2018

Published In

Volume / Issue

  • 13 / 1

Start / End Page

  • e0189749 -

PubMed ID

  • 29324745

Pubmed Central ID

  • PMC5764249

Electronic International Standard Serial Number (EISSN)

  • 1932-6203

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0189749


  • eng

Conference Location

  • United States