Correction of congenital diaphragmatic hernia in utero. I. The model: intrathoracic balloon produces fatal pulmonary hypoplasia.
Publication
, Journal Article
Harrison, MR; Jester, JA; Ross, NA
Published in: Surgery
July 1980
A conical silicone rubber balloon was placed in the left hemithorax of fetal lambs and progressively inflated through an exteriorized catheter over the last trimester. Newborn lambs died of severe respiratory insufficiency, despite maximal resuscitation. The lungs were markedly hypoplastic with greatly reduced parenchymal mass and air capacity. This model of a progressively enlarging intrathoracic mass which produces severe pulmonary hypoplasia and fatal respiratory insufficiency simulates the pathophysiology of congenital diaphragmatic hernia in human neonates.
Published In
Surgery
EISSN
1532-7361
ISSN
0039-6060
Publication Date
July 1980
Volume
88
Issue
1
Start / End Page
174 / 182
Related Subject Headings
- Surgery
- Sheep
- Resuscitation
- Respiratory Insufficiency
- Radiography
- Pregnancy Trimester, Third
- Pregnancy
- Lung Volume Measurements
- Lung
- Infant, Newborn
Citation
APA
Chicago
ICMJE
MLA
NLM
Harrison, M. R., Jester, J. A., & Ross, N. A. (1980). Correction of congenital diaphragmatic hernia in utero. I. The model: intrathoracic balloon produces fatal pulmonary hypoplasia. Surgery, 88(1), 174–182.
Harrison, M. R., J. A. Jester, and N. A. Ross. “Correction of congenital diaphragmatic hernia in utero. I. The model: intrathoracic balloon produces fatal pulmonary hypoplasia.” Surgery 88, no. 1 (July 1980): 174–82.
Harrison MR, Jester JA, Ross NA. Correction of congenital diaphragmatic hernia in utero. I. The model: intrathoracic balloon produces fatal pulmonary hypoplasia. Surgery. 1980 Jul;88(1):174–82.
Harrison, M. R., et al. “Correction of congenital diaphragmatic hernia in utero. I. The model: intrathoracic balloon produces fatal pulmonary hypoplasia.” Surgery, vol. 88, no. 1, July 1980, pp. 174–82.
Harrison MR, Jester JA, Ross NA. Correction of congenital diaphragmatic hernia in utero. I. The model: intrathoracic balloon produces fatal pulmonary hypoplasia. Surgery. 1980 Jul;88(1):174–182.
Published In
Surgery
EISSN
1532-7361
ISSN
0039-6060
Publication Date
July 1980
Volume
88
Issue
1
Start / End Page
174 / 182
Related Subject Headings
- Surgery
- Sheep
- Resuscitation
- Respiratory Insufficiency
- Radiography
- Pregnancy Trimester, Third
- Pregnancy
- Lung Volume Measurements
- Lung
- Infant, Newborn