Antenatal intervention for congenital cystic adenomatoid malformation.


Journal Article

In 2 fetuses with congenital cystic adenomatoid malformation (CCAM) with hydrops, in-utero resection of the enlarged pulmonary lobe reduced mediastinal shift and allowed expansion of normal lung tissue in both cases. In case 1, the 27-week-gestation fetus died from severe hydrops after premature delivery. In case 2, fetal CCAM resection was completed at 23 weeks' gestation. At 30 weeks a girl was delivered with no evidence of pulmonary hypoplasia. Fetal surgery can now be entertained for otherwise fatal space-occupying intrathoracic lesions.

Full Text

Cited Authors

  • Harrison, MR; Adzick, NS; Jennings, RW; Duncan, BW; Rosen, MA; Filly, RA; Goldberg, JD; deLorimier, AA; Golbus, MS

Published Date

  • October 1990

Published In

Volume / Issue

  • 336 / 8721

Start / End Page

  • 965 - 967

PubMed ID

  • 1977005

Pubmed Central ID

  • 1977005

Electronic International Standard Serial Number (EISSN)

  • 1474-547X

International Standard Serial Number (ISSN)

  • 0140-6736

Digital Object Identifier (DOI)

  • 10.1016/0140-6736(90)92420-m


  • eng