A test of the tridimensional personality theory: association with diagnosis and platelet imipramine binding in obsessive-compulsive disorder.


Journal Article

We administered the Tridimensional Personality Questionnaire (TPQ) to a sample of 25 individuals with obsessive-compulsive disorder (OCD) and 35 normal controls. As predicted, OCD cases scored much higher on the harm avoidance dimension than normal controls. Findings for the novelty seeking and reward dependence dimensions were less dramatic, although compatible with the underlying theory. Despite a theoretical link between the harm avoidance dimension and serotonin-mediated neuropathways, we failed to find an association between this dimension and platelet imipramine binding in either OCD cases or controls.

Full Text

Cited Authors

  • Pfohl, B; Black, D; Noyes, R; Kelley, M; Blum, N

Published Date

  • July 1, 1990

Published In

Volume / Issue

  • 28 / 1

Start / End Page

  • 41 - 46

PubMed ID

  • 2165423

Pubmed Central ID

  • 2165423

Electronic International Standard Serial Number (EISSN)

  • 1873-2402

International Standard Serial Number (ISSN)

  • 0006-3223

Digital Object Identifier (DOI)

  • 10.1016/0006-3223(90)90430-a


  • eng