Gold-nanocrystal-enhanced bioluminescent nanocapsules.
Journal Article (Journal Article)
Metal-enhanced bioluminescence presents a great opportunity to achieve ultrasensitive analysis and imaging with low bioluminescent background and enhanced luminescence. We hereby report metal-enhanced bioluminescence based on bioluminescent protein nanocapsules conjugated with gold nanocrystals. Such gold-nanocapsule complexes exhibit near 10-fold enhancement in bioluminescent intensity and are effectively delivered into the cells with outstanding stability. This work offers a class of bioluminescent nanoparticles for imaging and other applications.
Full Text
Duke Authors
Cited Authors
- Du, J; Jin, J; Liu, Y; Li, J; Tokatlian, T; Lu, Z; Segura, T; Yuan, X-B; Yang, X; Lu, Y
Published Date
- October 13, 2014
Published In
Volume / Issue
- 8 / 10
Start / End Page
- 9964 - 9969
PubMed ID
- 25243486
Pubmed Central ID
- 25243486
Electronic International Standard Serial Number (EISSN)
- 1936-086X
International Standard Serial Number (ISSN)
- 1936-0851
Digital Object Identifier (DOI)
- 10.1021/nn504371h
Language
- eng