Hydrogel design of experiments methodology to optimize hydrogel for iPSC-NPC culture.

Journal Article (Journal Article)

Bioactive signals can be incorporated in hydrogels to direct encapsulated cell behavior. Design of experiments methodology methodically varies the signals systematically to determine the individual and combinatorial effects of each factor on cell activity. Using this approach enables the optimization of three ligands concentrations (RGD, YIGSR, IKVAV) for the survival and differentiation of neural progenitor cells.

Full Text

Duke Authors

Cited Authors

  • Lam, J; Carmichael, ST; Lowry, WE; Segura, T

Published Date

  • March 2015

Published In

Volume / Issue

  • 4 / 4

Start / End Page

  • 534 - 539

PubMed ID

  • 25378176

Pubmed Central ID

  • 25378176

Electronic International Standard Serial Number (EISSN)

  • 2192-2659

International Standard Serial Number (ISSN)

  • 2192-2640

Digital Object Identifier (DOI)

  • 10.1002/adhm.201400410


  • eng