Hydrogel design of experiments methodology to optimize hydrogel for iPSC-NPC culture.

Published

Journal Article

Bioactive signals can be incorporated in hydrogels to direct encapsulated cell behavior. Design of experiments methodology methodically varies the signals systematically to determine the individual and combinatorial effects of each factor on cell activity. Using this approach enables the optimization of three ligands concentrations (RGD, YIGSR, IKVAV) for the survival and differentiation of neural progenitor cells.

Full Text

Published version (via Digital Object Identifier)
Pubmed Central version

Duke Authors

Segura, Tatiana

Cited Authors

Lam, J; Carmichael, ST; Lowry, WE; Segura, T

Published Date

March 2015

Published In

Advanced Healthcare Materials

Volume / Issue

4 / 4

Start / End Page

534 - 539

PubMed ID

25378176

Pubmed Central ID

25378176

Electronic International Standard Serial Number (EISSN)

2192-2659

International Standard Serial Number (ISSN)

2192-2640

Digital Object Identifier (DOI)

10.1002/adhm.201400410

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