Physical exosome:exosome interactions.

Journal Article (Journal Article)

Exosomes are extracellular nanovesicles that mediate a number of cellular processes, including intracellular signalling. There are many published examples of exosome-exosome dimers; however, their relevance has not been explored. Here, we propose that cells release exosomes to physically interact with incoming exosomes, forming dimers that we hypothesize attenuate incoming exosome-mediated signalling. We discuss experiments to test this hypothesis and potential relevance in health and disease.

Full Text

Duke Authors

Cited Authors

  • Beit-Yannai, E; Tabak, S; Stamer, WD

Published Date

  • March 2018

Published In

Volume / Issue

  • 22 / 3

Start / End Page

  • 2001 - 2006

PubMed ID

  • 29377463

Pubmed Central ID

  • PMC5824382

Electronic International Standard Serial Number (EISSN)

  • 1582-4934

Digital Object Identifier (DOI)

  • 10.1111/jcmm.13479

Language

  • eng

Conference Location

  • England