Physical exosome:exosome interactions.
Published
Journal Article
Exosomes are extracellular nanovesicles that mediate a number of cellular processes, including intracellular signalling. There are many published examples of exosome-exosome dimers; however, their relevance has not been explored. Here, we propose that cells release exosomes to physically interact with incoming exosomes, forming dimers that we hypothesize attenuate incoming exosome-mediated signalling. We discuss experiments to test this hypothesis and potential relevance in health and disease.
Full Text
Duke Authors
Cited Authors
- Beit-Yannai, E; Tabak, S; Stamer, WD
Published Date
- March 2018
Published In
Volume / Issue
- 22 / 3
Start / End Page
- 2001 - 2006
PubMed ID
- 29377463
Pubmed Central ID
- 29377463
Electronic International Standard Serial Number (EISSN)
- 1582-4934
Digital Object Identifier (DOI)
- 10.1111/jcmm.13479
Language
- eng
Conference Location
- England